E.E.R: First US Diagnosed Ebola patient Thomas Eric Duncan dies at Dallas hospital

Ebola patient Thomas Eric Duncan in 2011. (AP Photo/Wilmot Chayee)

DALLAS — The first person to be diagnosed with Ebola in the United States died early Wednesday, officials with Texas Health Presbyterian Hospital announced.

"It is with profound sadness and heartfelt disappointment that we must inform you of the death of Thomas Eric Duncan this morning at 7:51 a.m.," the hospital said in a written statement."Mr. Duncan succumbed to an insidious disease, Ebola."

The Liberian citizen, who recently traveled from West Africa to Dallas to reunite with a long-lost son and girlfriend, had been in isolation at Texas Health Presbyterian since Sept. 28.

It wasn’t immediately known what would happen to his body, which could remain contagious for several days. Guidelines from the Centers for Disease Control and Prevention call for the remains to be immediately shrouded in plastic and double-bagged in leak-proof bags at the hospital, then promptly cremated or buried in an airtight casket.

Duncan’s death comes four days after his condition was downgraded from serious to critical. Over the weekend, he had begun receiving brincidofovir, an experimental antiviral drug which recently gained emergency approval from the FDA.

"He fought courageously in this battle," the hospital said. "Our professionals, the doctors and nurses in the unit, as well as the entire Texas Health Presbyterian Hospital Dallas community, are also grieving his passing. We have offered the family our support and condolences at this difficult time."

Duncan, 42, is also the first person known to die of Ebola in the United States. The highly contagious virus has killed more than 3,400 people in West Africa in 2014, the World Health Organization estimates.

Five Americans who were diagnosed with Ebola in Africa have returned to the U.S. for treatment since late July. Aid workers Kent Brantly, Nancy Writebol and Rick Sacra made full recoveries. WHO said one of its doctors was transported to Emory University Hospital in Atlanta on Sept. 9. No other details have been released. Ashoka Mukpo, a cameraman working for NBC News, arrived at the Nebraska Medical Center in Omaha for treatment on Monday.

Duncan’s illness and treatment have sparked controversy. He arrived in Dallas on Sept. 20 from Liberia, one of the hardest-hit areas of the outbreak.

Texas Health Presbyterian Hospital in Dallas has come under scrutiny for its handling of the Ebola case. (AFP Photo/Joe …

His neighbors in Monrovia told reporters that five days before his flight, Duncan helped a pregnant woman get to the hospital in a taxi. She was convulsing and vomiting. The woman died at home hours later, after being turned away from a crowded Ebola treatment ward.

It is unclear if Duncan knew the woman had Ebola, but Liberian government officials said they plan to prosecute him for lying on health forms he completed at the airport on Sept. 19.

Duncan answered “no” to questions about whether he had cared for an Ebola patient or touched the body of someone who had died in an area affected by Ebola.

CDC officials said Duncan, who was reportedly coming to Dallas to be with his fiancee, didn’t have a fever or symptoms of Ebola when he boarded his flight in Liberia.

Five days after arriving in Dallas, a friend drove Duncan to the emergency room at Texas Health Presbyterian. Hospital officials said he showed up in the middle of the night with a fever of 100.1 degrees, abdominal pain for two days, a sharp headache and decreased urination. The hospital said Duncan told them he had not experienced nausea, vomiting, or diarrhea — strong indicators of Ebola.

Federal guidelines published in August state that someone in Duncan’s condition and who was known to have been in West Africa should be placed in isolation and tested for Ebola. Instead, Duncan was given a prescription for antibiotics and sent home.

Hospital officials initially blamed a flawed records system for the mix-up but have since retracted that account. No other explanation has been given for how the Ebola diagnosis was overlooked.

Duncan’s condition had worsened by the time he was brought back to Texas Health Presbyterian two days after being discharged. He was reportedly throwing up as paramedics put him in the ambulance at the apartment complex where he had been living with family and friends.

Those paramedics are among seven health care workers who are now being monitored for Ebola symptoms. Three family members living in the apartment where Duncan stayed when he arrived in Dallas are being watched closely for signs of the disease.

An additional 38 individuals, including a man who was treated in the same ambulance after it was used to transport Duncan, are considered low-risk contacts, but they will be monitored for 21 days, the maximum period of time it may take for symptoms to appear.

Texas Health Presbyterian immediately isolated Duncan upon his second arrival. According to the Dallas Morning News, the hospital may have violated federal guidelines by delaying a blood test for Ebola.

According to the report, other testing and blood work was done first to rule out other causes. The Ebola test wasn’t performed and confirmed until two days after Duncan was placed in isolation.

Dr. Thomas Frieden, director of the CDC, called the mishandling a "teachable moment" and issued a nationwide alert to all hospitals updating them on how to appropriately respond to possible Ebola cases.